Risk of Type 2 Diabetes, Metabolic Dysfunction Associated Steatotic Liver Disease and Cardiovascular Disease in People Living with Polycystic Ovary Syndrome According to Disease Phenotype: An Analysis of Prospective Cohort and Multi-Organ Imaging Data from the UK Biobank.

In UK Biobank, women with PCOS had greater prevalence and incidence of type 2 diabetes, steatotic liver disease, and all-cause cardiovascular disease. Liver MRI showed more severe steatosis and higher fibroinflammation by cT1. These comorbidities are increased in older PCOS patients with a disease phenotype-specific pattern.