Randomized, Controlled Trial of the FGF21 Analogue Pegozafermin in NASH

In this phase 2b randomized controlled trial, treatment with FGF21 analogue pegozafermin, a novel therapy for treating NASH, led to improvements in liver fat and fibro-inflammation (liver disease activity) quantified by cT1 from baseline up to 24 weeks. These results support the advancement of pegozafermin into phase 3 development.