Quantitative MRCP metrics as imaging biomarkers to differentiate benign from malignant bile duct obstructions

Quantitative MRCP metrics, especially total biliary tree volume, effectively distinguished malignant from benign biliary obstructions. A volume ≥25 ml predicted malignancy with good accuracy (AUC 0.79). These findings support MRCP+ as a non-invasive, contrast-free tool for identifying cholangiocarcinoma, potentially aiding earlier diagnosis and improving patient outcomes.