Poor glycaemic control and ectopic fat deposition mediates the increased risk of non-alcoholic steatohepatitis in high-risk populations with type-2 diabetes: Insights from Bayesian-network modelling

Using a Bayesian-network model, this study shows that in high-risk adults with type 2 diabetes, excess liver fat, poor glycaemic control, and excess visceral fat raise NASH risk by 31%, 22%, and 20%, respectively, with important implications for the development of targeted interventions to prevent NASH in high-risk populations.