Increased serum miR-193a-5p during non-alcoholic fatty liver disease progression: diagnostic and mechanistic relevance

In LITMUS, serum miRNA profiling identified elevated miR-193a-5p with worsening fibrosis and higher NAS/SAF scores, replicated in an independent cohort. Findings support circulating miRNAs, especially miR-193a-5p, as noninvasive biomarkers to detect advanced NAFLD without a liver biopsy.