Genome-wide and Mendelian randomisation studies of liver MRI yield insights into the pathogenesis of steatohepatitis

GWAS study of cT1 (LiverMultiScan) in 14,440 UK Biobank participants identified SLC39A as a genetic variant associated with fibro-inflammatory liver disease. Findings highlight SLC39A8 as a potential drug target and reinforce cT1 as a genetics-informed biomarker.