Genetic risk accentuates dietary effects on hepatic steatosis, inflammation and fibrosis in a population-based cohort

Poor diet quality and specific genetic alleles are associated with steatotic liver disease. Diet has a much greater impact on hepatic steatosis in those at higher genetic risk, affecting both liver fat content and cT1 (a measure of fibrosis and inflammation). Thus, dietary interventions may yield greater benefit in genetically susceptible groups.