Feasibility of using contrast-free quantitative magnetic resonance imaging for liver sparing stereotactic ablative body radiotherapy

In liver metastases, functional liver volumes automatically segmented using cT1 maps were used to create liver-sparing plans, which significantly reduced the functional liver mean dose versus standard planning. This first demonstration of cT1-guided stereotactic ablative radiotherapy suggests a route to spare healthy liver, though validation in liver cancer cohorts is required.