Evidence of a Direct Effect of Myocardial Steatosis on LV Hypertrophy and Diastolic Dysfunction in Adult and Adolescent Obesity

Proton MRS (1H-MRS) and cardiac MRI showed that even in the absence of other comorbidities, adult and childhood obesity is related to cardiac steatosis. Higher myocardial triglyceride content relates to diastolic dysfunction, stronger in males. The findings suggest that cardiac steatosis occurs early in obesity and significantly affects childhood.